Formulation Scientist

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionPrimary Purpose Of Job (Job Summary)Conduct preformulation and formulation research to support the technical development of small molecule assets within Roche China (CICoR)’s portfolio.Principle Roles & Responsibilities / Accountabilities (Major functions of the position)In this role, you will serve as a functional expert for CICoR’s small molecules NCE projects, create innovative and efficient solutions to specific problems utilizing state-of-the-art technologies and in-depth scientific knowledge and experience. You will be responsible forPreformulation research, including compound pharmaceutical profiling, physicochemical property characterization, solid-state characterization and polymorph/salt/co-crystal screening for phase-appropriate solid form selection;Preclinical formulation development and supply, including support for efficacy, DMPK, and toxicology studies;Development of formulations and manufacturing processes for clinical studies; planning, coordination and supervision of cGMP production of clinical trial materials at CDMOYou will represent the formulation function on cross-functional project teams and technical development teams. You will be responsible for:Participation in discussion of, and advising the project teams on topics pertaining to formulation, including the assessment of NCE developability from a preformulation and formulation perspectiveDevising and executing plans for formulation functional research activities according to project needsProviding regular updates on formulation functional research activities at the project team, TDT, site or cross-site governance levelEducation/QualificationsAdvanced degree in a scientific or relevant discipline (Ph.D. or equivalent) with at least 2 years or MS with at least 10 years of working experience in formulation, chemical engineering or related areas.Job Required CompetenciesThe ideal candidate should be proactive and self-motivated; a strong problem solver; and a good team player with good communication skills. The candidate should have:Sound knowledge in formulation theories and state-of-the-art technologies; demonstrated capability of conducting independent research; hands-on experience in operating, calibrating, maintaining and troubleshooting a wide range of instruments (sieving, blending, milling, dry granulation, wet granulations, tablet press, capsule filling, coating, packaging etc.) that are used in formulation developmentSound knowledge in the theories and technologies in preformulation and solid state science; demonstrated capability of conducting independent research; hands-on experience in operating, calibrating, maintaining and trouble-shooting a wide range of instruments (XRPD, DSC, TGA, PLM, DVS, IR, PSD, HPLC etc.) that are used in preformulation and solid state scienceWorking knowledge in SHE and cGMPProject management experience a plus; CRO CDMO management experience a plusFluency in both written and spoken EnglishWho we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.