Ph.D. Student and research assistant in CAR T cell engineering for cancer immunotherapy (m/f/d)

We offer A 3-year fully funded position with salary according to the German public service scale (TV-L), based on your qualifications and experience. A Part-time position (65%) A stimulating, internationally recognized research environment at one of Europe’s leading CAR T cell centers. Access to extensive national and international collaborations in cancer immunotherapy and glycoscience. Company pension scheme: We support your financial security in retirement.Flexitime: Allows you to organize your working hours flexibly.Comprehensive company sports programs: Our own gym (Milon circuit training) helps you stay fit and healthy.Own company day-care center with extended opening hours (5:30 – 18:00): To help you better balance work and family.Extensive training and further education at our own academy: We promote your personal and professional development.Your TasksGenetic engineering of CAR T cells with a focus on modulating glycosylation pathways.In-depth functional analyses in vitro, ex vivo, and in vivo using AML and MM models.Application of molecular biology techniques including vector cloning, Western blotting, and real-time PCR (qPCR).Project DescriptionYou will contribute to an exciting new research initiative — recently funded by Deutsche Krebshilfe and IMS— that aims to modulate glycosylation to improve the antitumor efficacy of CAR T cells. These projects investigates how glycan modifications affect CAR T cell function and how these insights can be applied to develop next-generation therapies against Acute Myeloid Leukemia (AML), Multiple Myeloma (MM) and other malignancies.The team is led by Dr. Andoni Garitano, MBA, who heads an interdisciplinary group with expertise in cellular immunotherapy, glycoengineering, and translational medicine.Your ProfileWe Are Seeking a Highly Motivated Candidate WhoHolds or is close to completing a Master’s degree in biomedicine, biology, biochemistry, biophysics, or a related discipline.Has hands-on experience in:T cell immunology and molecular biologyVector design and cloningWestern blot and real-time PCRMulti-color flow cytometry and data analysis (e.g., FlowJo, GraphPad Prism)Ideally has worked with mouse tumor models and holds FELASA.Is enthusiastic, results-oriented, well-organized, and eager to tackle scientific challenges creatively and independentlyThis Is What You Can Look Forward To Challenging, diverse and evolving area of responsibility Attractive salary according to TV-L incl. annual special payment Training and Continuing Education Retirement Pension Plan Company daycare center with extended opening hours Company sports program Flexible Working Hours JobBike Corporate Benefits Become part of the team: Apply now! Julia KrügerDirektionsassistenzTel: +49931 201 71292Dr. Andoni Garitano TrojaolaMedizinische Klinik und Poliklinik II – Hämatologie/OnkologieIn the case of a university degree from a non-EU country, a long version of the certificate evaluation from the Central Office for Foreign Education is required.Remuneration is in accordance with the relevant collective agreements. Severely disabled applicants will be given preference if they are otherwise equally qualified.Back Apply now