DTU - Technical University of Denmark

Postdoc in Development of Miniaturized Optoelectrical Platforms for Real-Time Monitoring of Brain Organoids - DTU Nanolab

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Job Description

Job DescriptionAre you keen on contributing to the development of strategies for the electrochemical monitoring of brain organoids by applying your microengineering skills? Here, we can offer you a unique opportunity to do exactly that in a dynamic research environment. In the CustomMade project, funded by the European Research Council, we are looking for a talented postdoc candidate focusing on the fabrication of novel miniaturized platforms with integrated 3D carbon microelectrodes and optical waveguides to enable simultaneous in situ optical stimulation of optogenetically modified neurons and electrochemical measurement of neurotransmitter release.You will be based at DTU Nanolab, where we conduct cross-disciplinary research and apply micro- and nanotechnology to a wide range of scientific disciplines and applications. The Biomaterial Microsystems group is a highly ambitious group, pursuing research on micro- and nanofabrication of 3D polymer and carbon structures and devices and their application in drug delivery, bioelectrochemistry and sustainable energy.Responsibilities And QualificationsIn the CustomMade project researchers at DTU Bioengineering, DTU Nanolab and three partner universities are pursuing ambitious research in the field of cell replacement therapy for Parkinson’s and Huntington’s disease. DTU Nanolab is responsible for the development of the hardware, which in this case is an optoelectronic platform for in vivo monitoring of brain organoids allowing for modeling of the diseases. The platform consists of two or multiple compartments which allows to monitor interactions between organoids in a connectoid configuration. In each compartment, 3D carbon electrodes are integrated which allows for electrochemical monitoring of the human neural stem cells in the organoid such as the dopaminergic differentiation.Your main contribution in this project will be the development of the optoelectrical platform with electrodes and optical waveguides. Given the size of the consortium, scalability of platform fabrication will be a central aspect that has to be considered. Your primary tasks will be to:plan and execute experimental researchdesign and fabricate micro- and nanoelectrode chips in the DTU Nanolab cleanroomcharacterize the micro- and nanoelectrodes with electrochemical methods develop an optoelectronic motherboard for optical actuation and electrochemical readoutcontribute with supervision of BSc, MSc and PhD studentsassist in experimental teaching activities (lab courses)As a formal qualification, you must hold a PhD degree (or equivalent). Extensive experience in cleanroom-based micro- and nanofabrication is essential. Furthermore, a theoretical and experimental background in electroanalysis is beneficial. You are expected to have a keen interest in biomedical applications and the ability to interact with researchers in a very interdisciplinary environment. Excellent communication and language skills are decisive to be considered for the position.We offerDTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.Salary and terms of employment The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union.The period of employment is 2 years. The desired starting date is 15 January 2026 (or according to mutual agreement). The position is a full-time position.You can read more about career paths at DTU here .Further informationFurther information may be obtained from Prof. Stephan Sylvest Keller, DTU Nanolab, suke@dtu.dk . You can read more about DTU Nanolab at www.nanolab.dtu.dk .If you are applying from abroad, you may find useful information on working in Denmark and at DTU at DTU – Moving to Denmark .Application procedure Your complete online application must be submitted no later than 20 November 2025 (23:59 Danish time). Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply now", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:Application (cover letter)CVAcademic Diplomas (MSc/PhD – in English)List of publications Applications received after the deadline will not be considered.All interested candidates irrespective of age, gender, disability, race, religion or ethnic background are encouraged to apply. As DTU works with research in critical technology, which is subject to special rules for security and export control, open-source background checks may be conducted on qualified candidates for the position.DTU Nanolab is a common infrastructure and research facility located at and fully owned by the Technical University of Denmark, DTU. The core facilities consist of a large cleanroom and a state-of-the-art electron microscopy center inaugurated in 2007. The research activities carried out at DTU Nanolab span from nano- and microfabrication with Silicon-based materials, carbon and polymers to the highly sophisticated analysis of nanoscale materials in hard and soft matter. Since 2018, DTU Nanolab is extended to provide expertise in soft matter from small molecule complexes to biological cells.Technology for peopleDTU develops technology for people. With our international elite research and study programmes, we are helping to create a better world and to solve the global challenges formulated in the UN’s 17 Sustainable Development Goals. Hans Christian Ørsted founded DTU in 1829 with a clear mission to develop and create value using science and engineering to benefit society. That mission lives on today. DTU has 13,500 students and 6,000 employees. We work in an international atmosphere and have an inclusive, evolving, and informal working environment. DTU has campuses in all parts of Denmark and in Greenland, and we collaborate with the best universities around the world.

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