Research Specialist in Membrane Spatial Biology

Do you want to contribute to top quality medical research?The Nanomedicine and Spatial Biology Lab at the Department of Physiology and Pharmacology, Karolinska Institutet, is seeking a talented research specialist to join our team. Our research focuses on investigating the roles of spatial organization in biological processes. To achieve this, we develop DNA nanotechnology-based tools to map and manipulate membrane protein nanodomains (e.g. Spratt, Dias et al., Nature Nanotechnology, 2024; Ambrosetti et al., Nature Nanotechnology, 2021; Shaw, Lundin et al., Nature Methods, 2014.)Description Of The Subject AreaMembrane proteins assemble into dynamic nanodomains that regulate receptor signaling and trafficking. Disruption of this spatial organization is implicated in diseases such as cancer and neurodegeneration. Nanodomains have the potential to be used as biomarkers and therapeutic targets. To realize this potential, we develop methods for large-scale, high-resolution mapping of the composition and nanoscale architecture of membrane protein nanodomains across physiological and disease states.Your missionWe are seeking a research specialist to drive innovative projects at the intersection of spatial biology and nanomedicine. The candidate will develop novel methodologies to analyze the spatial organization of proteins within cell populations and single cells.Eligibility RequirementsFor employment as Research Specialist at Karolinska Institutet, the eligibility requirements stated in the Guidelines for non-teaching positions at Karolinska Institutet are applied in relation to the established profile of employment.To be eligible for employment as a Research Specialist, in addition to holding a Degree of Doctor, PhD, or having a foreign degree deemed equivalent to a Swedish doctoral degree, the applicant must have demonstrated research expertise as well as have documented postdoctoral research experience.Assessment criteriaIt is particularly meritorious that the applicant has shown Expertise in DNA nanotechnology, computational biology, cell biology, and in vivo studies in zebrafish and mouse modelsExcellent communication skills and motivation to work collaborativelyAbility to work independently and manage multiple projects in parallelProficiency in spoken and written English It is meritorious that the applicant has shown Expertise in the design, production, and purification of DNA origami nanostructures, as well as in methods for analyzing cellular responses, including scRNA sequencing and advanced microscopyAfter an overall assessment of the expertise and merits of the applicants in relation to the subject area, Karolinska Institutet will determine which of them has the best potential to contribute to a positive development of the activities at KI.What do we offer?A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.Location: Solnahttps://ki.se/en/research/research-areas-centres-and-networks/research-groups/nanomedicine-and-spatial-biology-teixeira-labApplicationWe prefer that Your application is written in English, but You can also apply in Swedish. An application must contain the following documents: PhD certificate, resumé, qualifications and description of planned research, presented in accordance with Karolinska Institutet's qualifications portfolio.Welcome to apply at the latest November 9th 2025.The application must be submitted through the Varbi recruitment system.Want to make a difference? Join us and contribute to better health for all!Anställningsform: särskild visstidsanställning | Anställningens omfattning: heltid | Antal lediga befattningar: 1 | Sysselsättningsgrad: 100 % | Ort: Solna | Län: Stockholms län | Land: Sweden | Referensnummer: STÖD 2-4213/2025 | Kontakt: Ana Teixeira ana.teixeira@ki.se, Ana Teixeira ana.teixeira@ki.se, | Facklig företrädare: Helin Norberg, SACO helin.norberg@ki.se, Helin Norberg, SACO helin.norberg@ki.se, Bodil Moberg, ST bodil.moberg@ki.se, Bodil Moberg, ST bodil.moberg@ki.se, Elizabeth Valenzuela, SEKO elizabeth.valenzuela@ki.se, Elizabeth Valenzuela, SEKO elizabeth.valenzuela@ki.se, | Publicerat: 2025-10-24 | Sista ansökningsdag: 2025-11-09