Software Development Engineer

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionA healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us RocheWe are seeking a Senior Software Engineer with extensive GPU programming experience and a passion for bioinformatics and advanced algorithm development to create GPU-accelerated tools for DNA sequencing data analysis. In this role, you will design and implement high-performance computational algorithms—leveraging both traditional bioinformatics methods and deep learning models—optimized for the throughput and accuracy requirements of next-generation sequencing technologies. You will work closely with a multidisciplinary team of scientists and engineers to transform sequencing data into actionable biological insights.The Opportunity:Develop and optimize GPU-accelerated algorithms for real-time analysis of sequencing data, including basecalling, alignment, variant detection, and other genomic data processing tasksCollaborate with bioinformaticians and molecular biologists to translate computational challenges in genomics into robust, scalable software solutionsImplement and optimize neural network and other machine learning algorithms on GPU, adapting them for large-scale, high-throughput sequencing dataContribute to the design and implementation of novel sequence analysis algorithms, including signal processing, error correction, and statistical modelingAuthor dependable, readable, maintainable, and well-structured code in C++ and CUDA, following best practices for scientific and production softwareWork with the data scientists to accelerate existing algorithms or pipelinesStay current with advances in computational genomics, GPU computing, and algorithmic techniques; proactively research and integrate new methods as appropriateWho you are:Bachelor's degree in Computer Science, Computer Engineering, or a related field with 3+ years of relevant experience; MS/PhD is a plusStrong expertise in bioinformatics algorithm development, with emphasis on sequence analysis, variant calling, or genomic workflowsProficient in C++ object-oriented programming and GPU programming using CUDA, with experience in GPU-accelerated libraries like cuDNN or ThrustExtensive experience in systems programming for parallel Linux applications, including writing, debugging, and performance optimizationStrong understanding of machine learning and deep learning, especially applied to biological datasets, with hands-on experience in frameworks like PyTorch, TensorFlow, or JAXProficient in Python for rapid prototyping, data analysis, and integrating bioinformatics pipelines with custom algorithmsProven analytical, problem-solving, and collaborative skills, with effective communication for technical and scientific contextsRelocation benefits are not available for this posting.Who we areA healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let’s build a healthier future, together.Roche is an Equal Opportunity Employer.