Sr. Director, Program Management (Biotech/Pharma Experience Required)

About Our ClientOur client is pushing the boundaries of science and technology to revolutionize the way patients with brain disease are treated. They are seeking extraordinary individuals to join the team as they grow and advance their pipeline. About The RoleThe Senior Director, Program Management is responsible for leading operational execution and cross-functional alignment for one or more late-stage development programs. This is not a task-tracking role—they are looking for a strategic and proactive leader who thrives in fast paced, complex, matrixed environments and is passionate about bringing transformational CNS therapies to patients.

The ideal candidate will have strong CNS drug development experience, with a proven track record of leading cross-functional teams through pivotal trials, regulatory interactions, and commercial readiness planning. This role will partner closely with Program Team Leads, functional heads, and Executive leadership to ensure development activities are aligned, efficient, and financially sound. Responsibilities: Serve as the project manager on the core-team for one or more late-stage clinical development program, ensuring integrated execution across clinical, regulatory, CMC, quality, commercial, medical affairs, and other key functions.

Drive the creation and execution of comprehensive program plans that incorporate timelines, key milestones, budgets, resourcing, and risks. Own the development and day-to-day management of program budgets, including forecasting, tracking actuals, flagging variances, and partnering with finance and functional teams to ensure budget alignment and discipline. Facilitate high-impact cross-functional meetings, enabling clear decision-making, timely communication, and accountability for deliverables. Proactively identify challenges, dependencies, and risks—developing mitigation strategies and escalating where appropriate. Partner with Program Leadership and core-team members to support regulatory submission readiness, including coordination of INDs, NDAs, and global health authority interactions.

Prepare concise and insightful updates and presentations for internal governance and senior leadership forums. Champion a culture of ownership, urgency, and excellence within the program team and across the organization. Qualifications: Bachelor’s degree in life sciences or related field required; advanced degree (e. g. , MS, PhD, MBA) preferred. 10+ years of experience in Biotech/Pharma drug development, with 5+ years in a project or program management role supporting late-stage programs. CNS therapeutic area experience strongly preferred. Deep understanding of the drug development lifecycle, with hands-on experience supporting pivotal trials, regulatory submissions, and cross-functional development activities.

Proven ability to influence without authority, build trust across functions, and lead teams through ambiguity and change. Demonstrated experience in budget ownership or financial oversight for cross-functional programs. Strong strategic thinking, organizational, and interpersonal skills; comfortable interacting with senior leaders and managing complex, high-stakes projects. Experience with project management tools (e. g. , Smartsheet) and strong presentation development skills. Thrives in a fast-paced, mission-driven, and collaborative biotech environment. Ability and willingness to travel domestically up to 10%2025 Company benefits include: Medical, dental, vision, and life insurance401(k) plan:

The hiring company matches 50% of an employee’s eligible contribution, up to the first 6% of salary (up to 3% employer contribution)Company Equity (New Hire Awards, Annual Awards, ESPP)Annual paid time off: Accrued Vacation Days: 15 days per yearSick Days: 10 days per yearCompany Holidays: 13 days plus summer recharge week in July and winter shutdown in DecemberLeave of Absence: Paid Medical Leave, Paid New Parent Bonding Leave, Paid Family Leave, paid short-term and long-term disabilityDiscretionary year-end bonusSalary Range$ 265,000-$281,372Note: “We are not the EOR (Employer of Record) for this position.

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