Payroll Lead

Join us as we transform immunology and deliver medicines that help autoimmune patients get their lives back. argenx is preparing for multi-dimensional expansion to reach more patients through a rich pipeline of differentiated assets, led by VYVGART, our first-in-class neonatal Fc receptor blocker approved for the treatment of gMG, and with the potential to treat patients across dozens of severe autoimmune diseases.We are building a new kind of biotech company, one that maintains its roots as a science-based start-up and pushes our commitment to innovate across all corners of our business. We strive to inspire and grow our company, our partnerships, our science, and our people, because when we do, we deliver more for patients. About ArgenxAt argenx, we do things differently. We are a global immunology biotech company driven by science, collaboration, and a deep commitment to patients. Our culture empowers individuals to lead with expertise, not hierarchy. As we grow, we continue to redefine how biotech companies operate—through innovation, partnership, and purpose.Role OverviewThe Global Payroll Lead (GPL) is a key leader within the Finance team, accountable for payroll strategy and execution across all regions where argenx operates (EMEA, US, LATAM, APAC). The GPL ensures payroll is delivered with accuracy, compliance, and timeliness while driving global harmonization, process optimization, and automation. Acting as the primary point of expertise and escalation for payroll matters, this role partners closely with HR, Finance, IT, Legal, and external providers to ensure payroll not only meets compliance standards but also supports business growth and enhances the employee experience.This role is based in Belgium and requires 2x/week onsite presence.Roles And Responsibilities (non-exhaustive)Payroll Strategy & OperationsAccountable for accurate, timely, and compliant payroll delivery across all geographies.Oversees global payroll processing, approvals, reconciliations, and year-end activities.Ensures alignment with tax, labor law, and social security requirements in each country.Provides operational input into global people processes, compensation cycles, and employee lifecycle changes (e.g., onboarding, terminations, mobility). Risk & Compliance ManagementEnsures global payroll operations comply with SOX and other internal control frameworks.Partners with Internal Audit and Finance to ensure readiness for audits and inspections.Identifies payroll risks, ensures these are reflected in risk registers, and drives mitigations.Provides timely escalation and resolution of payroll issues impacting employees or compliance. Process Improvement & TransformationDrives global payroll harmonization, standardization, and scalability.Leads payroll technology initiatives (system upgrades, integrations, automation).Ensures consistency of processes across vendors and regions while maintaining local compliance.Promotes continuous improvement by sharing lessons learned and best practices across regions. Vendor & Stakeholder ManagementManages outsourced payroll vendors, ensuring service delivery against SLAs and KPIs.Oversees vendor selection, contracting, and governance in partnership with Procurement and Finance.Acts as primary point of escalation for vendor performance issues.Ensures strong alignment with HR, Finance, Legal, and IT stakeholders to deliver an integrated approach. Leadership & Team DevelopmentLeads, develops, and coaches a small global payroll team.Provides onboarding, goal setting, continuous feedback, and mentoring.Energizes and empowers team members, fostering a culture of accountability and excellence.Acts as a role model for the argenx cultural pillars: humility, co-creation, innovation, and empowerment.Skills And CompetenciesProven global payroll leadership experience in a complex, multi-country environment.Strong understanding of payroll compliance, regulations, and best practices across regions.Strategic thinker with the ability to translate operational challenges into sustainable solutions.Strong interpersonal, stakeholder management, and vendor management skills.Proactive problem solver with demonstrated ability to manage risks and resolve issues.Excellent organizational skills with the ability to manage complexity, prioritize, and maintain both a helicopter view and attention to detail.Strong people management and leadership skills; able to coach, inspire, and develop others.Excellent written and verbal communication skills; culturally sensitive and effective in global teams.Strong literacy in English (additional languages are an advantage).Education, Experience & QualificationsBachelor’s or Master’s degree in HR, Finance, Business, or equivalent experience.Minimum of 10 years of progressive payroll leadership experience in a global setting.Strong track record in managing outsourced payroll vendors and overseeing complex payroll operations.Experience with global payroll systems (e.g., ADP, SAP, Workday).Audit and compliance experienceIndustry experience in biotech, pharmaceuticals, or life sciences is a plus.What We OfferA dynamic, purpose-driven environment with global impact.Hybrid working model with flexibility.Opportunities for personal and professional growth.A culture of collaboration, innovation, and empowerment.At argenx, all applicants are welcomed in an inclusive environment. They will receive equal consideration for employment without discrimination on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, or any other applicable legally protected characteristics. argenx is proud to be an equal opportunity employer.Before you submit your application, CV or any other personal details to us, please review our argenx Privacy Notice for Job Applicants to learn more about how argenx B.V. and its affiliates (“argenx”) will handle and protect your personal data. If you have any questions or you wish to exercise your privacy rights, please contact our Global Privacy Office by email at privacy@argenx.com.