Max Delbrück Center

Postdoctoral Researcher – Bioengineering Anticancer Therapeutics (f/m/d)

Posted: 2 days ago

Job Description

The Max Delbrück Center for Molecular Medicine in the Helmholtz Association aims to transform tomorrow’s medicine through our discoveries of today. At locations in Berlin-Buch, Berlin-Mitte, Heidelberg and Mannheim, our scientists collaborate across disciplines to unravel the complexities of disease at the systems level – from molecules and cells to organs and entire organisms. Through strong academic, clinical, and industry partnerships, as well as global networks, we translate biological insights into innovations for early detection, individualized therapies, and disease prevention. Founded in 1992, the Max Delbrück Center is home to a vibrant community of 1,800 people from more than 70 countries.Our diverse workforce is a core strength that inspires creativity and innovation at the Max Delbrück Center (MDC).The MDC is committed to improving human health through transformative biomedical research. Our goal is to pioneer discoveries for preventing, treating, and ultimately curing disease.The Kudryashev Group at the MDC combines structural biology, biochemistry and computational methods to understand mechanisms of transmembrane signaling.The current position is a part of the Helmholtz Bioengineering Consortium, including genAI experts, structural and molecular biologists and clinicians to develop anticancer therapeutics by protein design.Job DescriptionAnalysis of the fundamental principles of protein–protein interactionsDesign of protein binders to specifically influence these mechanismsProduction of the designed proteinsBiochemical and functional testing:in vitroin cellsin organoidsContinuous optimization of the proteins using reinforcement learningGoal: development of preclinical candidatesLong-term goal: establishment of a biotech spin-offRequirementsPhD in Biochemistry, Molecular Biology or Biophysics, Bioengineering, or a related field.Experience in recombinant protein expression and purification.Experience with cryo-EM/ET would be an advantage.Strong motivation to conduct translational research and interest in entrepreneurship.Communication skills and ability to work collaboratively in a multidisciplinary environment.Knowledge of coding or scripting tools is an advantage.We offerinternational working environment with communication in English and Germaninteresting career opportunities and a range of opportunities for further qualification and trainingCompatibility of family and career certified by the workandfamily audit (“berufundfamilie audit”)Support for "New Berliners" through the MDC Welcome & Family OfficeYou Also Benefit Froma remuneration in accordance with the collective agreement for the federal public service (TVöD-Bund), including additional company pension schemesExciting science, outstanding scientific infrastructure, amazing colleaguesState-of-the-art facilities with a experimental labs, access to world-class instrumentation. For cryo-EM: TFS Titan Krios + K3, a TFS Aquilos2 for cryo-FIB milling, high performance IT infrastructure.International working environment in an interdisciplinary group, working language is English. a secure jobflexible working hours and childcare supportthe possibility of mobile workingan idyllic green campus, which is easily accessible by bicycle, public transport or carfree use of Nextbike from the Buch S-Bahn station to the campusSubsidy for the job ticket as well as discounts in the campus canteenOn-campus health and fitness centeradditional health benefits such as flu vaccination, eye test, ergonomics advice at the workplace

Job Application Tips

  • Tailor your resume to highlight relevant experience for this position
  • Write a compelling cover letter that addresses the specific requirements
  • Research the company culture and values before applying
  • Prepare examples of your work that demonstrate your skills
  • Follow up on your application after a reasonable time period

You May Also Be Interested In