Researcher in Biochemistry

Lund University was founded in 1666 and is repeatedly ranked among the world’s top universities. The University has around 47 000 students and more than 8 800 staff based in Lund, Helsingborg and Malmö. We are united in our efforts to understand, explain and improve our world and the human condition. Lund University welcomes applicants with diverse backgrounds and experiences. We regard gender equality and diversity as a strength and an asset.The division of Biochemistry and Structural Biology is part of the Centre for Molecular Protein Science (CMPS), Department of Chemistry. CMPS offers a creative and strong research environment with excellent infrastructure and several successful research groups that have attracted prestigious grants from the European Research Council and Wallenberg Foundation (see https://www.cmps.lu.se for more information)The current position is placed in Prof. Susanna Horsefield’s research group. The focus of the group’s research is to understand how membrane-bound proteins control transport of molecules across biological membranes in animal as well as plant cells. The aim of the research is to give detailed knowledge of the molecular mechanism of these transport processes and their regulation by obtaining structural models of membrane proteins and membrane protein complexes.Subject DescriptionThe project involves structural and functional studies of human membrane-bound water channels of high medical relevance. The goal is to obtain a deeper understanding of their physiological and pathophysiological role and generate structural information that can be used to develop drugs against for example cancer and neurodegenerative disease.Work dutiesThe work involves expression, purification and functional and structural characterization of human aquaporins on their own and in complex with interacting partners. You will work with methods for recombinant overproduction of membrane proteins in yeast, protein-protein interaction studies and structural determination using cryo-electron microscopy. You are also expected to take an active part in the overall research activity of the group, including sharing duties in the laboratory and responsibility for equipment as well as co-supervision of PhD- and undergraduate project students.Qualification RequirementsApplicants must have:A PhD or equivalent research qualification within biochemistry, structural biology or biomedicine or other subject relevant to the position.Minimum of 2-year postdoc experience within membrane protein structural biologyVery good oral and written proficiency in English.Significant practical experience and knowledge of expression, purification and characterization of human membrane proteinsDocumented practical experience of structural determination of membrane proteins using cryo-electron microscopyDocumented practical experience of protein-protein interaction studiesAssessment Criteria And Other QualificationsPractical experience of the following are considered as strong merits:Recombinant overproduction of human membrane proteins in yeastStructural studies of membrane proteins in complex with interacting partnersStructural and functional studies of human aquaporinsSupervision of degree student projectsConsideration will also be given to good collaborative skills, drive and independence, and how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.Terms of employmentThis is a full time position with a fixed-term employment of 11 months. The preferred start date is 2026-01-12 or as agreed.Contact person: Prof. Susanna Horsefield, susanna.horsefield@biochemistry.lu.se, +46 70 515 92 43Instructions On How To ApplyApplications shall be written in English and be compiled into a PDF-file containing:résumé/CV, including a list of publications,a general description of past research and future research interests (no more than three pages),contact information of at least two references,copy of the doctoral degree certificate, and other certificates/grades that you wish to be considered.Within the Faculty of Science research and education is conducted within Biology, Astronomy, Physics, Geosciences, Chemistry, Mathematics and Environmental Sciences. The Faculty of Science is organized into eight departments, gathered in the northern campus area in Lund. The Faculty of Science has approximately 1500 students, 360 PhD students and 700 employees.We kindly decline all sales and marketing contacts.Anställningsform: särskild visstidsanställning | Anställningens omfattning: heltid | Antal lediga befattningar: 1 | Sysselsättningsgrad: 100 | Ort: Lund | Län: Skåne län | Land: Sweden | Referensnummer: PA2025/3197 | Kontakt: Susanna Horsefield +46462224584, Susanna Horsefield +46462224584, Jessica Edwinsson , Jessica Edwinsson , | Facklig företrädare: OFR/ST:Fackförbundet ST:s kansli 046-2229362, OFR/ST:Fackförbundet ST:s kansli 046-2229362, SACO:Saco-s-rådet vid Lunds universitet kansli@saco-s.lu.se, SACO:Saco-s-rådet vid Lunds universitet kansli@saco-s.lu.se, SEKO: Seko Civil 046-2229366, SEKO: Seko Civil 046-2229366, | Publicerat: 2025-11-24 | Sista ansökningsdag: 2025-12-08