Jagiellonian University

Student studiów doktoranckich

Posted: 1 days ago

Job Description

Postdoctoral Position in Structural Biology and RNA Modifications! šŸ§¬šŸ”¬ Project: Molecular Analyses of Human Dihydrouridine Synthases Modifying tRNA. PI: Dr. Monika Gaik | Duration: 3 years, full-time. #Postdoc #Biology #RNA #Modifications #Analysis #Research #Science #OpportunityI am seeking a highly motivated postdoctoral researcher to investigate the function and assembly of human tRNA modifying enzymes. This project involves structural analysis of protein-tRNA complexes and the crystallization of target proteins bound to small-molecule fragments identified through fragment-based screening.ApplicationFor more details please send your CV to monika.gaik@uj.edu.pl šŸ“§šŸ“„ResponsibilitiesPreparation of DUS–tRNA complexes for single-particle cryo-EM.Structure-guided mutagenesis and in vitro functional assays.DUS crystallization and synchrotron measurements with semi-automated data analysis.QualificationsQualifications for a Research PositionEducational Requirements• PhD in Structural Biology, Biochemistry, Molecular Biology or related field.• The PhD degree must have been awarded no more than 7 years before the application date.Research and Publication Experience• Experience in cryo-EM or X-ray crystallography; expertise in protein purification required.• At least one first-author publication in a peer-reviewed journalEssential Skills• Strong teamwork and communication skills; proficiency in English.We Offer• A 3-year full-time postdoctoral position in a well-equipped and collaborative research environment.• Research Infrastructure with access to national cryo-EM facilities and international synchrotron beamlines.• Opportunities for professional development, independence, conference attendance and international collaborations.

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