A spokesman for the Hamas-run Civil Defence agency told the BBC that at least four people were killed, including three women, when a home belonging to the al-Banna family was bombed in the southern Sabra neighbourhood of Gaza City.
Strikes also reportedly hit a courtyard of al-Shifa hospital, in the western Rimal area.
The Civil Defence spokesman said another five people were killed, including two children and a woman, when a vehicle was hit on al-Qassam Street in Khan Younis.
Hamas put out a statement denying that its fighters had attacked Israeli troops and condemning the Israeli strikes.
"Hamas affirms that it has no connection to the shooting incident in Rafah and affirms its commitment to the ceasefire agreement," it said.
"The criminal bombardment carried out by the fascist occupation [Israeli] army on areas of the Gaza Strip represents a blatant violation of the ceasefire agreement."
The group's military wing meanwhile said it would postpone the return of a hostage's body it had recovered on Tuesday due to what it called Israeli "violations".
US Vice-President Vance told reporters in Washington: "The ceasefire is holding. That doesn't mean that there aren't going to be little skirmishes here and there."
"We know that Hamas or somebody else within Gaza attacked an [Israeli] soldier. We expect the Israelis are going to respond, but I think the president's peace is going to hold despite that," he added.
