PhD Position

PhD position in Translational Cancer Immunology Center for Molecular Medicine Cologne • AG Schlößer • Cologne Translational Immunology • Department of General, Visceral, Thoracic, and Transplantation Surgery • University of Cologne • Faculty of Medicine • University Hospital Cologne • Cologne, Germany The University of Cologne is one of the largest and oldest universities in Europe and one of the most important employers in our region. Our broad range of subjects, the dynamic development of our main research areas and our central location in Cologne make us attractive to students and researchers from around the world. We offer a wide range of career opportunities in science, technology, and administration.The Schlößer laboratory at the Center for Molecular Medicine Cologne works on translationally relevant mechanisms of immune evasion in solid cancers. The specific project focuses on B cells, which represent an important component of the tumor microenvironment and affect naturally occurring anti-tumor immune responses as well as cancer immunotherapies. While the production of antibodies is well characterized in the context of infectious diseases and cancer, many aspects of antigen-presenting B-cell functions need further investigation. We aim to elucidate the role of antigen-presenting B cells and B-cell mediated T-cell responses in immunosurveillance of gastric cancer. Your TasksComparison of immunopeptidome derived from different antigens and processed by different sources of antigen-presenting cellsCharacterization and phenotyping of induced tumor-specific T-cell responsesB-cell receptor and T-cell receptor sequencingIn vitro cytotoxicity experiments and testing the influence of specific drugs on the antigen-presenting capacity Your ProfileExcellent MSc degree in biology, biotechnology, or a related fieldStrong interest in translational research in immuno-oncologyExpertise in at least one of the following fields: Cell culture, bioinformatics or flow cytometryApplicants should be highly motivated, independent and have strong communication skillsKnowledge of immunological processes is a plus but not a prerequisite We offerA friendly and motivated work environment in a long-standing team of experienced biologistsClose relation with clinicians and a focus on translationally relevant research questionsSupport and training in several cutting-edge immune assays in a positive environment A joint graduate school of the medical faculty and the faculty of natural sciences (IPMM) The position is available from 01.01.2026 and is to be filled for three years with the possibility of an extension. The salary will be based on remuneration group 13 TV-L of the pay scale for the German public sector. According to the standards in Germany, PhD-students receive part-time contracts (65%). https://www.cmmc-uni-koeln.de/research/research-areas-projects/research-area-b/schloesser-assoc-rg-45 Please send your application to: hans.schloesser@uk-koeln.de BrancheKrankenhäuser und GesundheitseinrichtungenBeschäftigungsverhältnisSonstiges