Staff Scientist

Join the forefront of groundbreaking research at the Beckman Research Institute of City of Hope, where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.The Chintan Parekh Lab is seeking a highly motivated and skilled Staff Scientist to join the Pediatrics basic science research group. This role is crucial for advancing our discovery programs by enabling the generation of high-quality, reproducible data across both genomics and proteomics platforms.You will be a hands-on laboratory specialist with expertise in Next-Generation Sequencing (NGS) library construction. This position requires exceptional attention to detail and a proactive approach to establishing cutting-edge laboratory protocols.To learn more about Dr. Chintan Parekh please visit here .Key Responsibilities For This Role Include Next-Generation Sequencing (NGS) Library Preparation (Main Focus): You will independently perform the end-to-end preparation of complex NGS libraries from diverse sample types (e.g., cells, tissues). This includes executing established protocols for various sequencing assays, such as Transcriptomics (RNA-sequencing or RNA-seq), Epigenetics (ATAC-sequencing or ATAC-seq and Cleavage Under Targets and Release Using Nuclease or CUT&RUN), and Genetics (Exome Sequencing or WES). You will also manage quality control steps (e.g., concentration, fragment analysis) and troubleshooting of library preparation workflows. Assay Development and Protocol Establishment: You will be required to establish, optimize, and formally document new laboratory protocols for cutting-edge and newly published sequencing assays to expand the team's capabilities. You will also evaluate and integrate new reagents, kits, and technologies to improve library preparation efficiency and quality. Mass Spectrometry Sample Preparation: You will prepare biological samples (e.g., protein lysates, fractionated samples) for subsequent Mass Spectrometry (MS) analysis.Your Qualifications Should Include The Staff Scientist must possess, at a minimum, the U.S. equivalent Bachelor's or Master's degree in an appropriate discipline, and will often have a Ph.D. or other doctoral level degree. Direct, hands-on experience with some form of Next-Generation Sequencing (NGS) library preparation (e.g. RNA-seq, ATAC-seq, etc.) is required Excellent organizational skills with meticulous attention to detail and data integrity, and the ability to work independently and manage multiple projects simultaneously in a fast-paced environment.City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location.City of Hope is an equal opportunity employer.To learn more about our Comprehensive Benefits, please CLICK HERE